CNS Depressants
Drugs affecting the central nervous system - sedatives, hypnotics, and anxiolytics
Alprazolam
Alprazolam
Use:
Anxiety disorders, panic disorder
Mechanism:
Enhances GABA-A receptor activity
Clonazepam
Clonazepam
Use:
Seizure disorders, panic disorder, anxiety
Mechanism:
Enhances GABAergic neurotransmission by binding to benzodiazepine receptors
Diazepam
Diazepam
Use:
Anxiety, muscle spasm, seizures, alcohol withdrawal
Mechanism:
Enhances GABA-A receptor activity
Lorazepam
Lorazepam
Use:
Anxiety, insomnia, seizures, sedation
Mechanism:
Enhances GABAergic neurotransmission via benzodiazepine receptors
Midazolam
Midazolam
Use:
Procedural sedation, anesthesia premedication, status epilepticus, ICU sedation
Mechanism:
Enhances GABA-A receptor activity
Phenobarbital
Phenobarbital
Use:
Seizures, status epilepticus, sedation
Mechanism:
Enhances GABA-A receptor activity, prolongs chloride channel opening
Medical Disclaimer
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