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Albuterol
Albuterol Sulfate
Use:
Asthma, COPD, bronchospasm
Mechanism:
Selective beta-2 adrenergic receptor agonist causing bronchodilation
Alfatradiol
Alfatradiol
Use:
Menopausal vasomotor symptoms,Osteoporosis prevention in postmenopausal women,Weight management in certain populations
Mechanism:
Alfatradiol selectively binds to estrogen receptors; acts as an agonist in bone and uterus, antagonist in breast tissue, thereby reducing estrogen-dependent proliferation while preserving bone density.
Amoxicillin
Amoxicillin
Use:
Bacterial infections (respiratory, skin, ENT)
Mechanism:
Inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins
Aspirin
Acetylsalicylic Acid
Use:
Pain relief, fever reduction, anti-inflammatory, cardiovascular protection
Mechanism:
Irreversibly inhibits COX-1 and COX-2 enzymes, reducing prostaglandin synthesis
Acyclovir
Acyclovir Sodium
Use:
Herpes simplex, varicella-zoster, shingles
Mechanism:
Inhibits viral DNA synthesis by competing with deoxyguanosine triphosphate
Alendronate
Alendronate
Use:
Osteoporosis prevention and treatment, Paget's disease
Mechanism:
Inhibits osteoclast-mediated bone resorption by binding to hydroxyapatite
Allopurinol
Allopurinol
Use:
Chronic gout, hyperuricemia, prevention of tumor lysis syndrome
Mechanism:
Inhibits xanthine oxidase, reducing conversion of hypoxanthine to xanthine to uric acid
Amlodipine
Amlodipine Besylate
Use:
Hypertension, angina, coronary artery disease
Mechanism:
Blocks L-type calcium channels in vascular smooth muscle, causing vasodilation
Amoxicillin-Clavulanate
Amoxicillin-Clavulanate Potassium
Use:
Bacterial infections including beta-lactamase producing organisms
Mechanism:
Amoxicillin inhibits cell wall synthesis; clavulanate inhibits beta-lactamases
Amphetamine-Dextroamphetamine
Amphetamine/Dextroamphetamine
Use:
ADHD, narcolepsy
Mechanism:
Increases release of dopamine and norepinephrine, blocks reuptake
Atenolol
Atenolol
Use:
Hypertension, angina, post-MI, atrial fibrillation
Mechanism:
Selective beta-1 adrenergic receptor antagonist
Atomoxetine
Atomoxetine
Use:
ADHD
Mechanism:
Selective norepinephrine reuptake inhibitor
Atorvastatin
Atorvastatin Calcium
Use:
Hyperlipidemia, cardiovascular disease prevention
Mechanism:
Inhibits HMG-CoA reductase, reducing cholesterol synthesis
Azithromycin
Azithromycin Dihydrate
Use:
Respiratory infections, STIs, atypical pneumonia
Mechanism:
Inhibits bacterial protein synthesis by binding to 50S ribosomal subunit
Abiraterone
Abiraterone Acetate
Use:
Metastatic castration-resistant prostate cancer
Mechanism:
Irreversibly inhibits CYP17 (17Îą-hydroxylase/C17,20-lyase), blocking androgen synthesis
Acitretin
Acitretin
Use:
Severe psoriasis
Mechanism:
Regulates keratinocyte differentiation and proliferation
Adalimumab
Adalimumab
Use:
Rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, Crohn's disease, ulcerative colitis, psoriasis
Mechanism:
Binds TNF-alpha, preventing interaction with TNF receptors and reducing inflammation
Adenosine
Adenosine
Use:
Paroxysmal supraventricular tachycardia (PSVT), diagnostic aid
Mechanism:
Slows AV node conduction and interrupts reentry pathways via adenosine receptors
Albendazole
Albendazole
Use:
Parasitic worm infections, neurocysticercosis, echinococcosis
Mechanism:
Binds to beta-tubulin, inhibits microtubule polymerization in parasites
Alprazolam
Alprazolam
Use:
Anxiety disorders, panic disorder
Mechanism:
Enhances GABA-A receptor activity
Alteplase
Alteplase
Use:
Acute ischemic stroke, acute MI, acute PE
Mechanism:
Recombinant tissue plasminogen activator (tPA), converts plasminogen to plasmin, lysing fibrin clots
Amiodarone
Amiodarone
Use:
Life-threatening ventricular arrhythmias, atrial fibrillation
Mechanism:
Blocks potassium channels (prolongs repolarization), also has Class I, II, IV effects
Amitriptyline
Amitriptyline Hydrochloride
Use:
Depression, neuropathic pain, migraine prophylaxis, insomnia
Mechanism:
Inhibits reuptake of serotonin and norepinephrine; anticholinergic and antihistaminic effects
Amphotericin B
Amphotericin B
Use:
Severe systemic fungal infections
Mechanism:
Binds to ergosterol in fungal cell membrane, forms pores causing cell death
Anastrozole
Anastrozole
Use:
Hormone receptor-positive breast cancer (postmenopausal)
Mechanism:
Non-steroidal aromatase inhibitor, blocks estrogen synthesis
Anidulafungin
Anidulafungin
Use:
Candidemia, esophageal candidiasis, invasive candidiasis
Mechanism:
Inhibits beta-1,3-D-glucan synthase, disrupts fungal cell wall
Apixaban
Apixaban
Use:
Atrial fibrillation stroke prevention, DVT/PE treatment and prevention
Mechanism:
Direct factor Xa inhibitor
Apremilast
Apremilast
Use:
Psoriatic arthritis, plaque psoriasis, oral ulcers in Behçet's disease
Mechanism:
Inhibits PDE4, increasing cAMP and reducing inflammatory mediators
Aripiprazole
Aripiprazole
Use:
Schizophrenia, bipolar disorder, MDD adjunct, irritability in autism
Mechanism:
Partial agonist at D2 and 5-HT1A; antagonist at 5-HT2A receptors
Atezolizumab
Atezolizumab
Use:
NSCLC, small cell lung cancer, urothelial carcinoma, triple-negative breast cancer
Mechanism:
Blocks PD-L1, preventing interaction with PD-1 and restoring anti-tumor immunity
Atovaquone-Proguanil
Atovaquone/Proguanil
Use:
Malaria prevention and treatment
Mechanism:
Atovaquone disrupts mitochondrial electron transport; Proguanil inhibits dihydrofolate reductase
Aztreonam
Aztreonam
Use:
Gram-negative infections, safe in penicillin allergy
Mechanism:
Inhibits bacterial cell wall synthesis by binding to PBP3
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