Learn Pharmacology
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Omeprazole
Omeprazole
Use:
GERD, peptic ulcer disease, Zollinger-Ellison syndrome
Mechanism:
Irreversibly inhibits H+/K+ ATPase in gastric parietal cells
Ondansetron
Ondansetron Hydrochloride
Use:
Chemotherapy-induced nausea, postoperative nausea, radiation-induced nausea
Mechanism:
Selective 5-HT3 receptor antagonist blocking serotonin peripherally and centrally
Oseltamivir
Oseltamivir Phosphate
Use:
Influenza A and B treatment and prophylaxis
Mechanism:
Inhibits viral neuraminidase, preventing viral release from infected cells
Oxybutynin
Oxybutynin
Use:
Overactive bladder (urge incontinence, urgency, frequency)
Mechanism:
Antimuscarinic agent, relaxes bladder smooth muscle by blocking M3 receptors
Octreotide
Octreotide
Use:
Acromegaly, carcinoid tumors, VIPomas, esophageal varices
Mechanism:
Synthetic somatostatin analog that inhibits growth hormone, glucagon, insulin, and GI hormones
Olanzapine
Olanzapine
Use:
Schizophrenia, bipolar disorder, agitation
Mechanism:
Antagonizes dopamine D1-4, serotonin 5-HT2, muscarinic, H1, alpha-1 receptors
Omalizumab
Omalizumab
Use:
Moderate-severe persistent asthma, chronic spontaneous urticaria
Mechanism:
Binds free IgE, preventing IgE binding to mast cells and basophils
Oxaliplatin
Oxaliplatin
Use:
Colorectal cancer
Mechanism:
Forms platinum-DNA crosslinks, inhibiting DNA synthesis and replication
Oxycodone
Oxycodone Hydrochloride
Use:
Moderate to severe pain
Mechanism:
Mu-opioid receptor agonist in CNS
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