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Captopril
Captopril
Use:
Hypertension, Heart failure, Post-myocardial infarction
Mechanism:
Inhibits ACE, reducing conversion of angiotensin I to II, leading to vasodilation and decreased aldosterone.
Cephalexin
Cephalexin Monohydrate
Use:
Skin infections, streptococcal pharyngitis, UTI
Mechanism:
Inhibits bacterial cell wall synthesis by binding to PBPs
Cetirizine
Cetirizine
Use:
Seasonal/perennial allergic rhinitis, chronic urticaria
Mechanism:
Selective H1 receptor antagonist, minimal anticholinergic effects
Clotrimazole
Clotrimazole
Use:
Topical fungal infections, oral thrush, vaginal candidiasis
Mechanism:
Alters fungal cell membrane permeability by inhibiting ergosterol synthesis
Cyclobenzaprine
Cyclobenzaprine
Use:
Relief of muscle spasm associated with acute musculoskeletal conditions
Mechanism:
Central acting muscle relaxant, reduces tonic somatic motor activity via descending reticular activating system and spinal cord
Calcitonin
Calcitonin-Salmon
Use:
Postmenopausal osteoporosis, Paget's disease, hypercalcemia
Mechanism:
Inhibits osteoclast activity, reducing bone resorption
Cefazolin
Cefazolin
Use:
Surgical prophylaxis, skin infections, susceptible infections
Mechanism:
Inhibits bacterial cell wall synthesis
Ceftriaxone
Ceftriaxone Sodium
Use:
Serious infections, meningitis, gonorrhea, Lyme disease
Mechanism:
Inhibits bacterial cell wall synthesis
Cefuroxime
Cefuroxime
Use:
Respiratory infections, UTI, Lyme disease, surgical prophylaxis
Mechanism:
Inhibits bacterial cell wall synthesis
Celecoxib
Celecoxib
Use:
Osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, acute pain
Mechanism:
Selective COX-2 inhibitor reducing prostaglandin synthesis
Chlorthalidone
Chlorthalidone
Use:
Hypertension, edema
Mechanism:
Inhibits sodium-chloride cotransporter in distal convoluted tubule
Ciprofloxacin
Ciprofloxacin Hydrochloride
Use:
Urinary tract infections, respiratory infections, skin infections
Mechanism:
Inhibits bacterial DNA gyrase and topoisomerase IV
Clarithromycin
Clarithromycin
Use:
Respiratory infections, H. pylori, MAC infections
Mechanism:
Inhibits bacterial protein synthesis by binding to 50S ribosomal subunit
Capecitabine
Capecitabine
Use:
Colorectal, breast cancer
Mechanism:
Oral prodrug of 5-FU; converted to active form preferentially in tumor tissue
Carbamazepine
Carbamazepine
Use:
Seizures, trigeminal neuralgia, bipolar disorder
Mechanism:
Blocks sodium channels, reduces neuronal excitability
Carboplatin
Carboplatin
Use:
Ovarian, lung, head/neck cancers
Mechanism:
Forms platinum-DNA crosslinks, inhibiting DNA synthesis
Carvedilol
Carvedilol
Use:
Heart failure, hypertension, post-MI left ventricular dysfunction
Mechanism:
Non-selective beta blocker with alpha-1 blocking activity
Caspofungin
Caspofungin
Use:
Invasive candidiasis, aspergillosis (refractory), empiric antifungal therapy
Mechanism:
Inhibits beta-1,3-D-glucan synthase, disrupts fungal cell wall synthesis
Cefepime
Cefepime
Use:
Serious Gram-negative infections, febrile neutropenia, nosocomial pneumonia
Mechanism:
Inhibits bacterial cell wall synthesis
Cefotaxime
Cefotaxime
Use:
Serious infections, meningitis, gonorrhea
Mechanism:
Inhibits bacterial cell wall synthesis
Ceftaroline
Ceftaroline Fosamil
Use:
MRSA, community-acquired pneumonia, skin infections
Mechanism:
Inhibits bacterial cell wall synthesis; high affinity for PBP2a (MRSA)
Cetuximab
Cetuximab
Use:
Colorectal cancer, head and neck cancer
Mechanism:
Binds EGFR, blocking ligand binding and receptor activation
Cisplatin
Cisplatin
Use:
Testicular, ovarian, bladder, lung, head/neck cancers
Mechanism:
Platinum compound that cross-links DNA, inhibiting replication
Clindamycin
Clindamycin
Use:
Anaerobic infections, toxoplasmosis, MRSA (skin), malaria
Mechanism:
Inhibits bacterial protein synthesis by binding to 50S ribosomal subunit
Clonazepam
Clonazepam
Use:
Seizure disorders, panic disorder, anxiety
Mechanism:
Enhances GABAergic neurotransmission by binding to benzodiazepine receptors
Clopidogrel
Clopidogrel
Use:
Prevention of atherothrombotic events in patients with ACS, MI, stroke, or PAD
Mechanism:
Irreversibly inhibits P2Y12 component of ADP receptors on platelet surface, preventing platelet activation and aggregation
Colchicine
Colchicine
Use:
Acute gout flares, gout prophylaxis, familial Mediterranean fever
Mechanism:
Binds to tubulin, disrupts microtubules, inhibits neutrophil chemotaxis and phagocytosis
Conjugated Estrogens
Conjugated Estrogens
Use:
Menopausal vasomotor symptoms, vulvovaginal atrophy, osteoporosis prevention
Mechanism:
Estrogen replacement: binds estrogen receptors, promotes cellular growth and development
Cyclophosphamide
Cyclophosphamide
Use:
Various cancers, autoimmune diseases
Mechanism:
Cross-links DNA strands, preventing cell division (prodrug requires hepatic activation)
Cyclosporine
Cyclosporine
Use:
Organ transplant rejection prophylaxis, rheumatoid arthritis, psoriasis
Mechanism:
Inhibits calcineurin, blocking T-cell activation and IL-2 production
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