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Salbutamol
Salbutamol
Use:
Acute asthma exacerbations,COPD exacerbations,Exercise‑induced bronchospasm
Mechanism:
Selective activation of β2‑adrenergic receptors leading to smooth muscle relaxation and bronchodilation.
Salmeterol
Salmeterol
Use:
Bronchial asthma maintenance therapy,Chronic obstructive pulmonary disease (COPD) maintenance therapy,Pulmonary hypertension (off-label)
Mechanism:
Selective agonist of β2-adrenergic receptors in airway smooth muscle, increasing cAMP and causing bronchodilation
Sertraline
Sertraline Hydrochloride
Use:
Depression, anxiety disorders, OCD, PTSD
Mechanism:
Selective serotonin reuptake inhibitor, increasing serotonin levels in synaptic cleft
Sildenafil
Sildenafil
Use:
Erectile dysfunction, pulmonary arterial hypertension
Mechanism:
Inhibits PDE5, increasing cGMP in smooth muscle, causing vasodilation
Simvastatin
Simvastatin
Use:
Hyperlipidemia, cardiovascular disease prevention
Mechanism:
Inhibits HMG-CoA reductase, reducing cholesterol synthesis
Sumatriptan
Sumatriptan
Use:
Acute migraine, cluster headache
Mechanism:
Selective 5-HT1B/1D receptor agonist, causes vasoconstriction and inhibits neuropeptide release
Sacubitril-Valsartan
Sacubitril/Valsartan
Use:
Heart failure with reduced ejection fraction (HFrEF)
Mechanism:
Sacubitril inhibits neprilysin (increases natriuretic peptides); valsartan blocks AT1 receptors
Semaglutide
Semaglutide
Use:
Type 2 diabetes, obesity, cardiovascular risk reduction
Mechanism:
GLP-1 receptor agonist; increases insulin secretion, decreases glucagon, delays gastric emptying
Sorafenib
Sorafenib
Use:
Hepatocellular carcinoma, renal cell carcinoma, thyroid cancer
Mechanism:
Inhibits multiple kinases (RAF, VEGFR, PDGFR, KIT)
Sotalol
Sotalol
Use:
Ventricular arrhythmias, atrial fibrillation/flutter
Mechanism:
Non-selective beta-blocker with potassium channel blocking (prolongs repolarization)
Spironolactone
Spironolactone
Use:
Heart failure, hypertension, edema, hyperaldosteronism, acne
Mechanism:
Aldosterone antagonist; blocks mineralocorticoid receptors
Succinylcholine
Succinylcholine
Use:
Rapid sequence intubation, muscle relaxation for surgery
Mechanism:
Depolarizing neuromuscular blocker: binds nicotinic receptors, causes sustained depolarization
Sugammadex
Sugammadex
Use:
Reversal of rocuronium and vecuronium neuromuscular blockade
Mechanism:
Encapsulates rocuronium/vecuronium molecules, rapidly reversing neuromuscular blockade
Sunitinib
Sunitinib
Use:
Renal cell carcinoma, GIST, pancreatic NET
Mechanism:
Inhibits multiple receptor tyrosine kinases (VEGFR, PDGFR, KIT, FLT3)
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