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Tamsulosin
Tamsulosin
Use:
Benign prostatic hyperplasia (BPH) symptoms
Mechanism:
Selective alpha-1A adrenergic antagonist, relaxes smooth muscle in prostate and bladder neck
Timolol Eye Drops
Timolol
Use:
Open-angle glaucoma, ocular hypertension
Mechanism:
Reduces aqueous humor production
Tiotropium
Tiotropium Bromide
Use:
COPD, asthma (maintenance)
Mechanism:
Long-acting muscarinic antagonist (LAMA) causing bronchodilation
Tramadol
Tramadol Hydrochloride
Use:
Moderate to moderately severe pain
Mechanism:
Weak mu-opioid receptor agonist; inhibits reuptake of serotonin and norepinephrine
Trazodone
Trazodone Hydrochloride
Use:
Depression, insomnia
Mechanism:
Antagonizes serotonin receptors and inhibits serotonin reuptake
Tacrolimus
Tacrolimus
Use:
Organ transplant rejection prophylaxis
Mechanism:
Inhibits calcineurin, preventing T-cell activation and cytokine production
Tamoxifen
Tamoxifen
Use:
Hormone receptor-positive breast cancer
Mechanism:
Competitively binds estrogen receptors; agonist in bone/endometrium, antagonist in breast
Temozolomide
Temozolomide
Use:
Glioblastoma, anaplastic astrocytoma, metastatic melanoma
Mechanism:
Methylates DNA at O6 and N7 positions of guanine, causing DNA damage
Tenofovir Disoproxil Fumarate
Tenofovir DF
Use:
HIV-1 infection, chronic hepatitis B
Mechanism:
Nucleotide analog that inhibits HIV reverse transcriptase
Terbinafine
Terbinafine
Use:
Onychomycosis, tinea infections
Mechanism:
Inhibits squalene epoxidase, blocking ergosterol synthesis
Teriparatide
Teriparatide
Use:
Severe osteoporosis, glucocorticoid-induced osteoporosis
Mechanism:
Recombinant PTH (1-34) that stimulates new bone formation by osteoblasts
Testosterone
Testosterone
Use:
Male hypogonadism, delayed puberty
Mechanism:
Replacement of endogenous testosterone
Ticagrelor
Ticagrelor
Use:
Prevention of thrombotic cardiovascular events in ACS or history of MI
Mechanism:
Reversibly binds to P2Y12 receptor, preventing ADP-mediated platelet activation and aggregation
Tirzepatide
Tirzepatide
Use:
Type 2 diabetes mellitus, chronic weight management
Mechanism:
Dual GIP and GLP-1 receptor agonist: increases insulin secretion, decreases glucagon, slows gastric emptying, reduces appetite
Tizanidine
Tizanidine
Use:
Muscle spasticity
Mechanism:
Central alpha-2 adrenergic agonist, reduces spasticity by increasing presynaptic inhibition
Tocilizumab
Tocilizumab
Use:
Rheumatoid arthritis, giant cell arteritis, cytokine release syndrome
Mechanism:
Binds IL-6 receptors, blocking IL-6-mediated inflammation
Topiramate
Topiramate
Use:
Seizures, migraine prophylaxis
Mechanism:
Multiple: blocks sodium channels, enhances GABA, inhibits carbonic anhydrase, antagonizes glutamate
Trastuzumab
Trastuzumab
Use:
HER2-positive breast cancer, gastric cancer
Mechanism:
Binds HER2 receptor, inhibiting proliferation and inducing antibody-dependent cytotoxicity
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