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22 drugs found
Starting with D, browse below for more

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Showing drugs starting with D

Diphenhydramine

Diphenhydramine

Antihistamines (H1 Blockers, First Generation)BEGINNER

Use:

Allergic reactions, insomnia, motion sickness, EPS treatment

Mechanism:

Competitive H1 receptor antagonist; anticholinergic and sedative properties

⭐ 10 points

Diltiazem

Diltiazem Hydrochloride

Calcium Channel BlockersINTERMEDIATE

Use:

Hypertension, angina, atrial fibrillation/flutter rate control

Mechanism:

Non-dihydropyridine CCB; blocks L-type calcium channels in heart and vessels

⭐ 15 points

Donepezil

Donepezil

Cholinesterase InhibitorsINTERMEDIATE

Use:

Mild to severe Alzheimer's disease

Mechanism:

Reversibly inhibits acetylcholinesterase, increasing acetylcholine in CNS

⭐ 15 points

Doxycycline

Doxycycline Hyclate

TetracyclinesINTERMEDIATE

Use:

Respiratory infections, Lyme disease, acne, STIs, malaria prophylaxis

Mechanism:

Inhibits bacterial protein synthesis by binding to 30S ribosomal subunit

⭐ 15 points

Duloxetine

Duloxetine Hydrochloride

Antidepressants (SNRIs)INTERMEDIATE

Use:

Depression, anxiety, neuropathic pain, fibromyalgia, chronic musculoskeletal pain

Mechanism:

Inhibits serotonin and norepinephrine reuptake

⭐ 15 points

Dabigatran

Dabigatran Etexilate

AnticoagulantsADVANCED

Use:

Atrial fibrillation stroke prevention, DVT/PE treatment/prevention

Mechanism:

Direct thrombin (factor IIa) inhibitor

⭐ 20 points

Dantrolene

Dantrolene Sodium

Skeletal Muscle Relaxants (Direct-Acting)ADVANCED

Use:

Malignant hyperthermia, neuroleptic malignant syndrome

Mechanism:

Inhibits calcium release from sarcoplasmic reticulum, reducing muscle contraction

⭐ 20 points

Dapagliflozin

Dapagliflozin

SGLT2 InhibitorsADVANCED

Use:

Type 2 diabetes, heart failure, chronic kidney disease

Mechanism:

Inhibits SGLT2, increasing urinary glucose excretion

⭐ 20 points

Daptomycin

Daptomycin

Cyclic Lipopeptide AntibioticsADVANCED

Use:

Complicated skin infections, bacteremia, endocarditis (MRSA/MSSA)

Mechanism:

Binds to bacterial membrane, causes rapid depolarization and cell death

⭐ 20 points

Denosumab

Denosumab

RANK Ligand (RANKL) InhibitorsADVANCED

Use:

Osteoporosis, bone loss from cancer, giant cell tumor

Mechanism:

Binds RANKL, preventing osteoclast formation, function, and survival

⭐ 20 points

Desmopressin

Desmopressin

Antidiuretic Hormone AnalogsADVANCED

Use:

Diabetes insipidus, nocturnal enuresis, hemophilia A, von Willebrand disease

Mechanism:

Synthetic vasopressin analog that increases water reabsorption in kidneys

⭐ 20 points

Dexamethasone

Dexamethasone

CorticosteroidsADVANCED

Use:

Severe inflammation, cerebral edema, chemotherapy-induced nausea, COVID-19

Mechanism:

Potent glucocorticoid with minimal mineralocorticoid activity

⭐ 20 points

Dexmedetomidine

Dexmedetomidine

Alpha-2 Agonists (Sedatives)ADVANCED

Use:

ICU sedation, procedural sedation

Mechanism:

Selective alpha-2 adrenergic agonist in CNS, reduces sympathetic outflow

⭐ 20 points

Dexrazoxane

Dexrazoxane

Cardioprotective Agents / ChelatorsADVANCED

Use:

Anthracycline-induced cardiomyopathy prevention, anthracycline extravasation

Mechanism:

Iron chelator that prevents anthracycline-induced free radical formation

⭐ 20 points

Diazepam

Diazepam

BenzodiazepinesADVANCED

Use:

Anxiety, muscle spasm, seizures, alcohol withdrawal

Mechanism:

Enhances GABA-A receptor activity

⭐ 20 points

Digoxin

Digoxin

Cardiac GlycosidesADVANCED

Use:

Heart failure, atrial fibrillation

Mechanism:

Inhibits Na+/K+ ATPase, increasing intracellular calcium in cardiac myocytes

⭐ 20 points

Dobutamine

Dobutamine

Inotropes (Beta-1 Agonists)ADVANCED

Use:

Cardiogenic shock, heart failure exacerbation, stress echocardiography

Mechanism:

Selective beta-1 agonist increasing cardiac contractility and output

⭐ 20 points

Docetaxel

Docetaxel

Taxanes (Microtubule Inhibitors)ADVANCED

Use:

Breast, lung, prostate, gastric, head/neck cancers

Mechanism:

Stabilizes microtubules, preventing depolymerization and cell division

⭐ 20 points

Doripenem

Doripenem

Carbapenem AntibioticsADVANCED

Use:

Complicated intra-abdominal infections, complicated UTI, pneumonia

Mechanism:

Inhibits bacterial cell wall synthesis by binding to PBPs

⭐ 20 points

Doxorubicin

Doxorubicin

Anthracycline AntibioticsADVANCED

Use:

Breast, lung, ovarian, lymphomas, sarcomas, leukemias

Mechanism:

Intercalates DNA, inhibits topoisomerase II, generates free radicals

⭐ 20 points

Dupilumab

Dupilumab

Interleukin Inhibitors (IL-4/IL-13)ADVANCED

Use:

Atopic dermatitis, asthma, chronic rhinosinusitis with nasal polyps

Mechanism:

Blocks IL-4 and IL-13 signaling by binding IL-4 receptor alpha

⭐ 20 points

Dutasteride

Dutasteride

5-Alpha Reductase InhibitorsADVANCED

Use:

Benign prostatic hyperplasia

Mechanism:

Inhibits BOTH 5-alpha reductase type I and II, blocking conversion of testosterone to DHT

⭐ 20 points
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