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Benazepril
Benazepril
Use:
Hypertension,Heart failure,Post-myocardial infarction
Mechanism:
Inhibits angiotensin-converting enzyme, reducing conversion of angiotensin I to angiotensin II, leading to vasodilation, decreased aldosterone secretion, reduced systemic vascular resistance and preload.
Baclofen
Baclofen
Use:
Muscle spasticity due to MS, spinal cord injury, or other spinal disorders
Mechanism:
GABA-B receptor agonist, inhibits monosynaptic and polysynaptic reflexes at spinal level
Budesonide
Budesonide
Use:
Asthma, COPD, Crohn disease (oral formulation)
Mechanism:
Potent glucocorticoid with anti-inflammatory effects
Bupropion
Bupropion
Use:
Depression, smoking cessation, ADHD (off-label)
Mechanism:
Inhibits reuptake of norepinephrine and dopamine (NDRI)
Bendamustine
Bendamustine
Use:
Chronic lymphocytic leukemia, non-Hodgkin lymphoma
Mechanism:
Bifunctional alkylating agent with purine analog properties
Bevacizumab
Bevacizumab
Use:
Colorectal, lung, kidney, glioblastoma, ovarian, cervical cancers
Mechanism:
Binds VEGF-A, inhibiting angiogenesis and tumor vascularization
Bleomycin
Bleomycin
Use:
Hodgkin lymphoma, testicular cancer, squamous cell carcinomas
Mechanism:
Induces DNA strand breaks via free radical formation
Bortezomib
Bortezomib
Use:
Multiple myeloma, mantle cell lymphoma
Mechanism:
Reversibly inhibits 26S proteasome, causing cell cycle arrest and apoptosis
Brimonidine
Brimonidine
Use:
Open-angle glaucoma, ocular hypertension, rosacea (topical)
Mechanism:
Reduces aqueous humor production and increases uveoscleral outflow (eye); vasoconstriction (rosacea)
Bumetanide
Bumetanide
Use:
Edema, heart failure, renal disease
Mechanism:
Inhibits Na-K-2Cl cotransporter in thick ascending loop of Henle
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